|Also Known As||Olmifon, CRL-40028|
|Stacks Well With|
|Half-life||1 hours (then 12-15 hours as Modafanil)|
Adrafinil is a legal synthetic nootropic supplement with a similar chemical structure as Modafinil. The role of this smart drug is to help users stay alert and awake without experiencing hyperactivity. Other user benefits include: enhanced learning abilities, better memory, and improved brain functions overall. For additional Adrafinil details, take a look at the full report below.
Adrafinil is a precursor drug to Modafinil and a potent nootropic brain stimulant sold online without a prescription. Once consumed, it metabolizes in the liver, creating a high concentration of Modafinil in the body. Although Adrafinil possess stimulating qualities, it doesn’t cause hyperactivity. It increases wakefulness and alertness, which is perfect for students, those who work late night shifts, and patients struggling with narcolepsy.
Adrafinil helps to improve the mood, motivation, and energy levels by increasing the power of Histamine, Dopamine, and Norepinephrine in the brain. These are essential neurotransmitters responsible for keeping you awake and present.
By preventing Dopamine breakdown, Adrafinil effectively reduces the stress, normalizes the sleep cycle, and boosts the user’s mood. Also known as Olmifon, Adrafinil belongs to the group of Eugeroics or wakefulness-promoting agents.
Brief History of Adrafinil
Adrafinil was first developed in the late 1970’s by the French pharmaceutical company called Group Lefon. Originally named Olmifon, the drug was initially used to treat narcolepsy in patients who are not able to regulate their sleep patterns.
This is precisely the reason why Adrafinil is referred to as a wakefulness agent – because it stimulates the central nervous system. While there are no particular regulations regarding the use of Adrafinil in the U.S. and Canada, the drug is sold as an over-the-counter dietary supplement and a nootropic cognitive enhancer.
That being said, the drug is not without flaw. The conversion of Adrafinil to Modafinil can burden the liver while the effects stay active in the system for a prolonged period of time. However, negative side-effects are quite rare, so Adrafinil can be used freely for retaining focus and amplifying cognitive abilities, as well as performance.
In other words, this type of supplementation is intended for those struggling to stay awake and find a healthy balance between work/studyin) and other daily activities. Adrafinil helps you concentrate on the work ahead for long hours, while enhancing your performance in the process.
The role of this smart drug is to help users stay alert and awake without experiencing hyperactivity
Ingredients: How Adrafinil Works?
As previously mentioned, Adrafinil is a synthetic nootropic with Modafinil as one active ingredient. The good thing is that the formula is free off dairy, gluten, egg, peanuts, fish, soybeans, and wheat whilst other ingredients include:
· Silicon Dioxide
· Magnesium Stearate
So how does Adrafinil work? This unique compound works in the central nervous system acting on the androgenic part of the brain responsible for releasing adrenaline. Once Adrenaline is synthesized in the liver and converted into Modafinil, the drug increases the body’s levels of hypocretin.
Adrafinil is able to mimic the “fight or flight” response thanks to hypocretin, a neurotransmitter that makes us feel alert and awake. Since narcolepsy patients suffer from a lack of hypocretin in the brain, Adrafinil is the best solution for treating this condition.
What is more interesting, the increase of hypocretin affects the production of Dopamine, Histamine, and Norepinephrine. To put it simply, Adrafinil has an influence over other hormones and neurotransmitters that regulate physical and mental energy levels.
However, most nootropic users prefer Adrafinil due to its effects on Glutamate receptors. The drug actually modulates these memory receptors and therefore improves their neural connection or communication, which leads to enhanced memory and better cognitive performance.
Adrafinil Benefits and Effects
Given that Adrafinil has an almost identical structure as Modafinil, there are many scientific studies confirming the health benefits of both drugs. Here are some reviews of the key studies performed with this supplement.
Wakefulness and Cognitive Improvements
In a 2004 double-blind study on Modafinil’s effects on patients with narcolepsy, the treatment was found to be highly successful in sustaining wakefulness throughout the day without any insomnia issues as a result.
The patients were given 400-mg of Modafinil once a day along with a placebo or a Modafinil split-dose of 600-mg for 3 weeks. The 600-mg dosage was proven to be more effective in improving a person’s state of alertness, and the drug was well tolerated during the course of the treatment.
The study suggests that Modafinil significantly improved the patients’ executive functions, and that the drug is effective for sustaining wakefulness throughout the day, but only if an additional dose of 200-mg is taken during the midday.
Similarly, the stimulating effects of Adrafinil were observed in the study on nocturnal activity of the rhesus monkeys. The tests performed on ten monkeys in a safe and controlled environment showed that the nocturnal activity doubled at a dose of 60-mg and even quadrupled at 120-mg of oral Modafinil administration.
The effects similar to the daytime activity lasted for 36 hours with no particular recovery period or side effects noticed during the post treatment.
Behavior and Vigilance
Adrafinil’s effects on behavior and cognition were also observed in the study on aged canines. After only a single treatment, the results displayed:
· Increased movement
· A long-lasting increase in brain activity
· Cognitive enhancing potential
However, the drug also shows the positive effects in young and healthy people. In a 2005 parallel group study, a group of 60 healthy student volunteers randomly received 100 or 200-mg of Modafinil and a placebo. Two hours later, researchers tested their cognitive abilities in order to identify any potential changes.
While the group that received 200-mg was faster and performed better than the placebo group on the attention tests, the 100-mg group showed improvements in forwards digit span tasks. In general, both Modafinil groups improved their recognition patterns but it wasn’t until years later that the true potential of Modafinil was unlocked with further drug examination.
Antioxidative and Neuroprotective Effects
In 2012 a study was conducted to investigate the neuro-immune interaction of Modafinil. The goal was a complete review of Modafilin effects, benefits, risks, and overall significance of the drug.
The study revealed that Modafinil can be the ideal antipsychotic and anti-fatigue agent. At the end, the conclusion was: “Modafinil can be used by anyone, who wishes to work late, stay awake, enhance their cognitive reactions, or brighten their moods. Users may already be under a great level of stress, i.e. cancer patients or soldiers in a battle field.”
Adrafinil vs. Modafinil: What is the Difference?
Adrafinil is a predrug for Modafinil, meaning that it converts to Modafinil in the system. Modafinil makes the portion of this conversion and it’s the only active agent of Adrafinil. On the other hand, the rest is metabolized to the inactive Modafinilic acid.
“A novel study of screening and confirmation of Modafinil, Adrafinil and their metabolite Modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization” explored their differences “under electron impact ionization in gas chromatograph-mass spectrometer (GC-MSD) and electrospray ionization in liquid chromatograph-mass spectrometer (LC-MS/MS) by studying the fragmentation pattern of these drugs.”
The results concluded that both Modafinil and Adrafinil possess pharmaceutical properties similar to amphetamine. The only difference is that they don’t have negative side-effects like stimulants such as amphetamine may produce.
However, there are some differences between the two drugs, but they are quite minor. For instance, the 300-600-mg of Adrafinil is equal to approximately 200-mg of Modafinil. Also, the effects of Modafinil last significantly longer than Adrafinil. Therefore, Adrafinil is the perfect nootropic supplement, while the potent Modafinil is more suited for narcolepsy treatment.
Both Modafinil and Adrafinil possess pharmaceutical properties similar to amphetamine. The only difference is that they don’t have negative side-effects like stimulants such as amphetamine may produce.
Adrafinil Side Effects
Adrafinil is a synthetic drug, so there are some possible side effects. The common and mild side effects include:
· Sleep Issues
Eating may decrease Adrafinil’s effectiveness and increase the likelihood of these slightly discomforting events. Likewise, it’s best not to take the drug late in the day or in the evening.
Although it’s quite rare, Adrafinil consumption may produce hallucinations, chest pain, and accelerated heartbeat or fluttering, better known as heart palpitation.
Warning: Adrafinil is not recommended for people suffering from heart conditions and disorders. The consumption of this supplement may cause discomfort such as chest pains and other symptoms.
Please consult a doctor before taking Adrafinil. Only a physician can determine if the drug is safe for you to use and in what dosage.
Warning: Continuous use of Adrafinil should be strictly avoided because it can affect the liver.
The continuous use of this drug builds up the enzymes in the liver, which can lead to potential issues. If at any moment you feel discomfort after Adrafinil consumption, it’s recommended to immediately consult a doctor.
Additional Adrafinil Notes
Not all Adrafinil supplements on the market are real. In other words, you should learn to recognize the difference between the real nootropic and false Adrafinil. The best way to differentiate the two is by taking a close look at a few basic features.
The real and helpful Adrafinil supplement has a light color, which is mostly rosy, pinkish, and off-white shades. The product should quickly dissolve in the water, though if the Adrafinil is in crystalized form, you might note crystalline sediment on the bottom of the glass.
Also keep in mind that real Adrafinil can be odorless. However, some products have a specific sulfurous smell that diminishes over time. So don’t worry about the fragrance, but look at the color and solubility.
Adrafinil is considered safe as long as the drug is taken in the recommended dose of 100-300-mg per day. It takes approximately an hour to feel the effects of the drug, so it’s best to take it early in the morning.
The supplement should be consumed on a daily basis for no more than 2 weeks and the dosage should not exceed 600-mg. Keep in mind that the effects vary and depend solely on the individual user experience.
If you consider stacking Adrafinil with other nootropic products, you can take advantage of Caffeine, Kratom, Noopept, and Phenibut. These nootropics can enhance Adrafinil’s effects and bring better cognitive results. Not to mention the fact that stacking this drug with other nootropics can lower the risks of side effects.
As usual, nootropics from the racetam family can boost cognitive functions while also protecting the brain. You won’t have to worry about your energy levels, and you shouldn’t stack Adrafinil with nootropics such as Piracetam or Phenylpiracetam, because the effects might be too strong if you don’t reduce the dosage of Adrafinil.
When it comes to Adrafinil supplementation, user experience differs and depends largely on the individual biology. Personally, I occasionally use it while struggling with work and I get good results. It all started when I was trying to obtain my college degree and couldn’t keep up with the program, assignments, tests, and find some “me time.”
Adrafinil got me through college and continued to assist me during the stressful periods at work. I have a difficult time focusing and completing tasks on time, and this drug helped me to accomplish what I needed.
I would liken Adrafinil’s effects to drinking a lot of plain, dark, and strong coffee, just without side effects such as sweating, nervousness, and the uncontrolled chain of thoughts that excessive caffeine tends to cause. Instead, Adrafinil gave me the energy and focus to complete my mission and stay sane during the busiest time of my life. So I gladly recommend that you try Adrafinil if you can relate to my story.
Where to Buy Adrafanil
Where can one buy nootropics? This is a frequent question, since it’s very important to find the real deal in a sea of online hoaxes. For starters, you can check out Amazon for affordable, yet effective Adrafinil nootropic supplements.
Here we raccommand a verified source you can take advantage of:
Adrafinil is a great nootropic and a truly helpful solution in times of need. It can efficiently increase attention, memory, and cognitive performance overall. The effects wear off quickly, but the brain retains the enhanced capabilities for some time.
Also, Adrafinil is practically harmless if you take it as recommended. All in all, we give it 5 stars for a synthetic drug, especially considering that it stacks nicely with other nootropic cognitive enhancers.