Also Known As NALT, N-Acetyl L-      Tyrosine
  • Natural, Stimulant
Good for
  • Memory, Learning, Energy, Focus, Mood
Stacks Well With
Dosage 500- 1000 mg
Half-life 1-3 hours

L-Tyrosine is a multifaceted supplement that may improve your mood, memory, focus, and cognitive abilities while reducing the harmful effects of stress. This naturally occurring amino acid promotes a healthy brain chemical structure, elevates mental clarity, enhances memory, and may even be able to control weight.


L-Tyrosine is an amino acid known as Tyrosine, which is commonly used as a supplement. The “L” stands for the term “Levo” and it serves to point out that the product is derived from natural sources rather than being a synthetic compound made in the laboratory. The natural version of L-Tyrosine is believed to be better because it can be absorbed faster than synthetic products.

L-Tyrosine is a non-essential amino acid, which means that our body is capable of producing Tyrosine on its own. It was first discovered in 1846 in casein, the main protein found in cheese. Nevertheless, while our body naturally produces Tyrosine, some people can benefit from supplementing, especially those struggling with stress and social anxiety.

Although L-Tyrosine supplementation helps to regulate the production of hormones, it’s also crucial for the creation of melanin. In addition, L-Tyrosine shares quite a few chemical similarities to thyroid hormones, i.e. it can improve the body’s fat-burning processes and suppress the appetite.

How Does L-Tyrosine Work?

Considering that it’s an amino acid, L-Tyrosine is used by the cells in the body to synthesize proteins. The body makes Tyrosine from Phenylalanine, another amino acid that can be found in dairy products as well as meats, fish, nuts, beans, eggs, wheat, and oats.

However, Phenylalanine has a special role and that is to make neurotransmitters such as dopamine, noradrenaline, and adrenaline among others. Still, the quantity our body produces is not always enough, and it may need a boost of L-Tyrosine supplement that will provide more “building blocks” for these catecholamines to be produced.

The neurotransmitters in question are important for a balanced mood and healthy stress responses. L-Tyrosine gives your body the energy it might be lacking, increases mental focus, and improves stress responses along with the mood.

As it’s also related to thyroid hormones, due to adrenaline and thyroid relations, it’s commonly found in fat loss supplements in smaller quantities.

Catecholamines Function

Catecholamines are chemicals our body produces, among which we can separate the three most important ones:

• Dopamine
• Epinephrine (Adrenaline)
• Norepinephrine (Noradrenaline)

Although some of these chemicals are commonly referred to as neurotransmitters, some of them are also classified as hormones. The difference is that neurotransmitters carry chemical messages from cell to cell (neurons) within the brain, whereas hormones share the same purpose, but throughout the body’s tissues and organs. So they are considered both hormones and neurotransmitters, due to a variety of functions they have throughout the entire body.

Catecholamines help to ease the communication between neurons and have a significant influence on mental functions, including the mood. Their role is of extreme importance, especially in “fight or flight” situations. When we find ourselves in stressful or dangerous circumstances, these components induce a state of heightened alertness and enhanced physical and mental energy.

Moreover, the catecholamines are also required for maintaining a balanced weight. They possess powerful fat-burning properties, hence, with an adequate supplementation of these hormones the proper fat-burning process begins.

Though L-Tyrosine has a lot of other benefits, its main purpose is closely related with advantages of acting as “block builders” of catecholamines

L-Tyrosine Benefits & Effects

According to the studies, the synthesis of catecholamines is regulated by several enzymes and therefore a simple consumption of Tyrosine won’t increase their levels in the body. This is precisely why L-Tyrosine supplementation matters, because it supplies the body with what it needs to produce them. Though L-Tyrosine has a lot of other benefits, its main purpose is closely related with advantages of acting as “block builders” of catecholamines.

Mood & Stress Response

Several studies conducted on animals and humans suggest L-Tyrosine supplementation can protect against both mental and physical manifestations of stress. In a study on chronically stress mice, the stress effects were drastically reduced when the L-Tyrosine supplement was introduced.

“The findings indicate the neuroendocrine network plays an important role in chronic stress, and that L-tyrosine supplementation has therapeutic effects.”

Furthermore, increased environmental stress due to extreme weather conditions can be treated with Tyrosine. This type of situations can be quite stressful to the point of disrupting behavior and depleting the brain’s catecholaminergic neurotransmitters. Not to mention the consequences of long exposure to cold and hypoxia.

However, study results showed a considerable decrease of all symptoms, including the mood and performance impairment. In addition, the research recommends that tyrosine should be evaluated for use in a variety of deeply stressful situations.

Improved Cognitive Functions

In a 1995 study, sleep-deprived individuals received an L-Tyrosine supplement to test their cognitive performance during extended wakefulness. The results of this study displayed that participants receiving L-Tyrosine performed better in cognitive and psychomotor tasks, proving once again that “Tyrosine is useful in counteracting performance decrements during episodes of sustained work coupled with sleep loss.”

Similar Tyrosine improvements were noted in a 1999 study on the effects of Tyrosine on cognitive task performance. A group of 21 cadets were studied during a demanding military combat training course for a week. The findings confirmed that the group supplied with a tyrosine-rich drink performed better on a memory and a tracking task. Additionally, the L-Tyrosine supplementation reduced blood pressure in cadets.

Working Memory Enhancement

A 2013 study tested the effects of L-Tyrosine on the working memory of adults. Participants were given challenging mental tasks and while those who took supplemental tyrosine did perform better on difficult and demanding tasks, there was no improvement on easier task challenges. The final conclusion was that L-Tyrosine can replete cognitive resources, but only when more control is needed.

These findings are consistent with those in animals, which also showed that L-Tyrosine can preserve and improve mental functions during high-stressed situations. And as we are all different, “Tyrosine’s modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function”. Meaning, people struggling with Tyrosine deficiency can benefit more from L-Tyrosine supplementation.

As it’s a confirmed fact that L-Tyrosine rises the levels of dopamine in the brain, Tyrosine is believed to promote cognitive flexibility. The evidence from a study on proactive vs. reactive control during task switching performance support the idea that L-Tyrosine can facilitate cognitive flexibility.

As it’s a confirmed fact that L-Tyrosine rises the levels of dopamine in the brain, Tyrosine is believed to promote cognitive flexibility

Better Focus & ADHD Treatment

Probably some of the most interesting study findings on L-Tyrosine and dopamine effects are those presented in a 2011 study on both adult and pediatric ADHD patients. The total percentage of patients showing significant improvement was 77%, whereas 67% of participants achieved a substantial progress with only amino acid precursors of serotonin and dopamine.

Further studies indicated L-Tyrosine supplementation has positive effects on pharmaceutical ADHD medication. Nevertheless, many individuals without disorders reported that L-Tyrosine supplementation improved their focus and mental clarity.

Weight Regulation

Initially, Tyrosine was used as a pre-workout supplement for its fat-burning and energy boosting properties. The use of Tyrosine can do wonders for sports performance and weight loss according to recent information.

Tyrosine’s effects and properties include:

• Stress relief in both life and during a workout regime
• Decreases signs of depression, mental fatigue, and burnout
• Improves workout intensity, prevents overtraining, and maximizes body composition
• Enhances mental alertness and cognitive performance
• It’s an effective treatment for addicts and drug withdrawal
• It’s useful for premenstrual syndrome (PMS) symptoms

Basically, anything that can support catecholamine release will boost your energy. While L-Tyrosine supplements only work when the brain is running low, it’s recommended to include them in other workout and fat-burner supplements.

On the other hand, L-Tyrosine has also been shown to improve exercise capacity and appetite in anorexic mice. Tyrosine restored food consumption with no effects on the weight, since there was a 22% increase in activity.

Tyrosine administration significantly improves food consumption, activity performance, and cognitive behavior. Likewise, L-Tyrosine supplementation may improve exercise tolerance and fatigue, which makes it a perfect treatment for eating disorders, apart from being a beneficial workout tool.

L-TyrosineL-Tyrosine Dosage

When it comes to a proper L-Tyrosine dosage, it all depends on the individual body weight and personal reasons for L-Tyrosine consumption. A number of studies and research point out that Tyrosine intake may amount to numbers as high as 12 grams per day.

Although the generally accepted daily range is around 1 and 5 grams, most studies on L-Tyrosine effects included a dosage of 10 grams per day, divided into 5x2g doses, or 100-150 mg per kg of bodyweight.

These doses are considered to be safe if taken up to three months. Then again, there are no studies on the effects of long-term use and a higher dosage of L-Tyrosine. However, some research conducted on mice suggests that there might be complications from higher dosages, still, there are no such human studies to compare and examine potential consequences.

When to Take It?

The only deciding factor for when to take it should be what you wish to use it for. For example, taking one 500mg capsule of Tyrosine per day can relieve the symptoms of anxiety and improve your mood.

The same amount is also recommended for treating mental fatigue. L-Tyrosine is best to be taken 15 minutes before food consumption or any other liquids besides water. Whereas the best anti-stress and exercise results are achieved by taking L-Tyrosine 30 to 60 minutes before the training session.

That said, if this dosage causes stomach problems, you can split the dose into two parts. Therefore, you can take one-half of L-Tyrosine 60 minutes before the workout, and the other half 30 minutes before you begin exercising.

The effects should be visible for about one to three hours after consumption. Given that L-Tyrosine is a stimulant, it shouldn’t be taken before sleep.

L-Tyrosine Side Effects

L-Tyrosine is absolutely safe if taken in recommended doses. To correctly determine the appropriate dosage according to your bodyweight and treatment purpose, consult with your physician.

In general, the commonly reported side effects are usually mild and temporary. Also, they include symptoms such as headaches, migraine, and upset stomach. The only thing to remember is that you need to avoid L-Tyrosine supplementation if you are taking medicine for high blood pressure.

L-Tyrosine should not be taken by individuals with thyroid disease and women who are pregnant or nursing, since there are no studies proving that it is safe for them.

On the same note, people suffering from phenylketonuria (PKU), a rare inherited disorder, should avoid L-Tyrosine supplementation, unless recommended by a doctor. People with PKU should stay away from phenylalanine in their diets and since Tyrosine is made of phenylalanine, only a physician can determine if they need more Tyrosine and how much.

L-Tyrosine Stacking

L-Tyrosine is a great supplement with a wide range of nootropic effects. This is why Tyrosine is an excellent base for nootropic stacking and it works well with Noopept and Racetams. For antianxiety effects, it’s recommended that you stack Tyrosine with Aniracetam and Citicoline for better results.

Combining L-Tyrosine with other nootropics improves all aspects of brain function, including memory, mood, stress resistance, brain repair, blood flow to the brain, and overall mental performance, while protecting neurons from any potential damage.

Where to Buy L-Tyrosine

Although it’s available in many retail stores, quality L-Tyrosine supplementation can be easily found online. We recommend affordable Amazon sources such as Pure Encapsulations – L-Tyrosine – Neurotransmitter Precursor for Mood and Memory capsules designed for cognitive, thyroid, and mood support.

Buy from Pure Encapsulations

If the plan is to improve endurance and energy during workouts, than BulkSupplements Pure L-Tyrosine Powder (500 grams) is the safest choice, as the brand guarantees pure and natural ingredients for a healthy and energized metabolism.

Buy from BulkSupplements

Of course, consider adding other nootropics to the mixture for efficiently boosting your physical and mental performance.


If looking for a natural solution to enhance and protect your cognitive abilities, especially from early signs of aging and brain deterioration that comes with. Therefore, L-Tyrosine supplements are the best choice to stay on the safe and smart side. The same applies for efficient workout sessions, as L-Tyrosine can eliminate signs of fatigue and prevent burnout.

As we can see from multiple studies, L-Tyrosine supplementation can help with various disorders from ADHD to chronically stressed individuals. Due to its stimulating effects on Catecholamines production, Tyrosine can help you perform better in different situations.

Still, it’s always better to stack L-Tyrosine with other nootropics to enhance its benefits and gain more physical and physiological advantages. Just pay attention to the dosage and feel free to consult your doctor if you have any doubts.


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