Also Known As Neuractiv, Neuromet, Hydroxypiracetam
  • Racetam
  • Ampakine
Good for
  • Memory
  • Learning
  • Mood
  • Creativity
  • Awareness
Stacks Well With  

Dosage 600 – 1500 mg
Half-life 10 hours

Oxiracetam falls under the category of Racetam compounds, along with Piracetam and Aniracetam. It is a powerful, safe, and highly effective nootropic which enhances the release of excitatory neurotransmitters and is used to enhance cognition.


Oxiracetam, also known as 4-hydroxy-2-oxo-pyrrolidine acetamide, is a type of highly potent man-made cognitive enhancer used to affect a broad range of cognitive processes and to improve numerous mental functions, such as memory, learning capacity, attention span, sensory perception, concentration, and logical thinking.

It is also considered to be a stimulant, as it helps increase alertness, motivation and mental energy. According to numerous clinical studies, it can even be used to protect brain health, and it is completely safe to use. It was first synthesized in the 1970s and it is a derivative of Piracetam, which is considered to be the original “smart drug”.

Such studies have shown that Oxiracetam can be a helpful substance when it comes to restoring memory, although no specific use has been approved by USFDA yet and it is still unregulated in the US, the UK, Australia and Canada.

Being a synthetic derivative of Piracetam, Oxiracetam differs from it in chemical structure as it has a single hydroxyl group, but has similar characteristics. Although, it is said to be 5 times stronger than Piracetam. Users usually describe its stimulatory properties as mild, without any feeling of agitation which can normally be experienced when using stimulants.

Although being primarily known to improve learning ability, memory capacity and other similar functions along with the potential to increase energy and alertness, this nootropic has also been studied as a potential cure for Alzheimer’s, dementia, and some other neurological diseases as well.

Oxiracetam has also been tested on animals, where it showed to be powerful in amnesia prevention induced by different anti-glutaminergic and anti-cholinergic compounds. It has been used to enhance memory formation in healthy mice and rats without any cognitive deterioration.

Oxiracetam Benefits and Effects

Oxiracetam is well known for its cognitive enhancement and mild stimulatory properties and it is one of the most popular substances of this kind. It is completely safe even when it comes to high dosages and is valued for its stackability properties. Let us now focus on each and every benefit that it brings separately.

Users usually describe its stimulatory properties as mild, without any feeling of agitation which can normally be experienced when using stimulants

Improves memory. – Oxiracetam is used to improve memory by simultaneously enhancing memory formation and memory retention, and by having positive effects on the recall speed. People most commonly use it when they take exams and when they study logic-related subjects such as math, but it can nevertheless be used when studying creative subjects, too.

Enhances logical thinking. – While people mostly use it to improve their memory and for studying purposes, Oxiracetam can reportedly also cause advancements in logical thinking, enhancing reasoning and analytical abilities.

Improves focus and concentration. – Oxiracetam shows great results in improving focus and concentration in users enabling them to stay motivated without losing attentiveness for longer periods of time. Even though other Racetam derivatives possess the same capability, Oxiracetam’s potency is by far the greatest, making it the students’ favorite choice.

Increases both physical and mental energy. – Oxiracetam is a mild stimulant which affects the central nervous system and increases our physical and mental energy without causing the feelings of anxiety that amphetamines usually create.

Enhances sensory perception. – Reportedly, many users have experienced enhancement in sensory perception, especially when it comes to sounds and visual perceptions by increasing left brain functions. It can make sounds become more clear and colors more vivid and with more contrast.

How Oxiracetam Works

Oxiracetam’s mechanisms of action are quite similar to Piracetam and Aniracetam, as they boost cognitive functions by stimulating particular neurotransmitters and adjusting the release of specific brain chemicals. It affects glutamatergic and cholinergic systems, modulating the release of neurotransmitters, glutamate, and acetylcholine.

Both of these neurotransmitters are essential for learning, memory and other cognitive functions. These effects are similar to other Racetam-class compounds, although they are, as already mentioned, far more powerful and long lasting.

Moreover, Oxiracetam also enhances communication among neurons especially in the hippocampal area. It works by releasing D-Aspartic acid and by affecting the metabolism of lipids, both of which improve neural signaling.

Oxiracetam has mild stimulatory effects on CNS since it belongs to a group of ampakines – compounds which interact with the glutamatergic AMPA receptors. Ampakines are stimulants which don’t possess side effects such as nervousness or sleepiness that are usually commonly attributed to amphetamines, Ritalin and caffeine.

Oxiracetam is a water soluble substance which is ingested in the gastrointestinal tract, peaking 1-3 hours after consumption. After about an hour, it crosses the blood-brain barrier and has a half-life of a maximum of 10 hours.

Oxiracetam works by releasing D-Aspartic acid and by affecting the metabolism of lipids, both of which improve neural signaling.

Oxiracetam Dosage

Although the majority of nootropics don’t have any or have only some minimal side effects, it is important for users to learn about the recommended dosage. Taking doses above the recommended ones can abolish the effects of Oxiracetam or cause side effects that are negative to some extent.

OxiracetamHowever, there is a broad range for dosages since every individual’s body has a different response to Oxiracetam. 600 mg is considered to be a minimum dose, and 1500 mg a maximum that should be taken per one day, in 2-3 dosing periods.

If it is your first time to take Oxiracetam, it is advised to start with very small doses. For optimal results, you should take a small amount when you wake up in the morning, then a few hours after that and finally once again in the evening.

Basically, there is no fixed rate when it comes to its dosage. Instead, you would have to experiment a bit, try it and see how it affects your body to figure out what dosage is the best for you.

There is still not enough evidence about whether taking Oxiracetam with food enhances or lowers its effects, however, it is recommended to be consumed an hour before you start studying. It comes in the form of powder and is said to be one of the tastiest nootropics thanks to its sweet flavor.

Oxiracetam Stacking

If you are not satisfied with the results of Oxiracetam supplementation or if you simply want to experiment further, you can always go for stacking with other cognitive enhancers to achieve even higher results.

What to stack with depends purely on whether you want to further improve the existing benefits that Oxiracetam provides or to improve the range of cognitive enhancements you experience.

If you have already made up your mind, read on to find out more about some of the most popular Oxiracetam stacks.

Aniracetam Oxiracetam Stack

Since Oxiracetam and Aniracetam are both ampakines, this stack does not offer almost any additional effects other than what Oxiracetam provides alone. However, they stack together extremely well since they both provide very strong cognitive improvements and mildly stimulating effects, while adding the benefit of anxiety reduction and mood elevation provided by Aniracetam.

Recommended dosage is: 800 mg Aniracetam and 800 mg Oxiracetam one to two times a day

Choline Oxiracetam Stack

It is always a good idea to combine Oxiracetam with Choline if you are already supplementing with Oxiracetam, since it is very important to maintain steady levels of Choline in your system if you are using Oxiracetam. This stack helps strengthen the effects of Oxiracetam and also helps prevent headaches which are most commonly reported as a side effect when using Oxiracetam for prolonged periods of time.

Recommended dosage is: 300 mg Alpha GPC and 800 mg Oxiracetam one to two times a day.

Pramiracetam Oxiracetam Stack

It is not a surprise that these two stack well since they both belong to the Racetam family of nootropics and Oxiracetam stacks well with other Racetams as well. Stacking these two together extends and improves the strong cognitive benefits of both of these supplements, while also providing a light CNS stimulation which helps improve mental focus and overall alertness.

Recommended dosage is: 200 mg Pramiracetam and 800 mg Oxiracetam one to two times a day.

Oxiracetam Side Effects

One of the reasons Oxiracetam is so popular is that it has almost no serious commonly reported side effects. Clinical studies have shown that it is not toxic and completely safe even in exceptionally high dosages. If supplemented per instructions, it has almost no significant side effects.

Having said all of this, it is important to mention that some users have reported headaches as a side effect which comes as no surprise since all Racetam-class supplements have this same problem.

However, headaches are most likely the result of high doses or the lack of choline in your system. If you have a problem with headaches while supplementing Oxiracetam, just try reducing the amount you take or simply add a Choline supplement to your regimen.

Some users have reported temporary digestion issues or gastric problems which are also ameliorated by lowering the amount of Oxiracetam. At last, since it is a stimulant, Oxiracetam sometimes disturbs the normal sleep cycle of some users. This can be prevented by simply ingesting it earlier during the day or lowering the dosage.

Oxiracetam Experience

Sensory Perception

Many users report increased sensory perception as the first effect they notice after using Oxiracetam. Most commonly visual and auditory perception is increased as well as the distinction between otherwise unnoticeable differences in visual and auditory perception.

Most users also report an increased and slightly altered awareness of the world around them. Sounds become more vibrant and colors deeper and more luscious. Also, many people said that they experienced a more profound connection with their immediate surroundings.

Learning and Memory

Memory is commonly affected in many users’ experiences as most people reported that they could remember what they studied more easily. Many users also reported an enhanced ability to remember names, dates, figures and facts, and some have even reported that they could remember their dreams vividly. Most people consider Oxiracetam as an excellent aid during exam preparations.

Logic and Reasoning Improvement

Oxiracetam is famed for its ability to improve logic abilities which comes as no surprise if you take a look at many different reports in which people praise Oxiracetam for improving their cognitive abilities. Users reported being able to think more clearly and much faster than usual. A lot of people reported an increased ability to solve mathematical, logical and analytical problems.

Focus and Concentration Enhancement

Oxiracetam is particularly popular with students since it improves memory, focus and understanding. People have reported increased alertness and wakefulness for long period of time, but without any mental fogginess. Overall, Oxiracetam is best at improving attention span, focus and concentration.

Where to Buy Oxiracetam

Since the market for nootropics has enjoyed substantial growth in recent years, it shouldn’t be a problem to find vendors who sell Oxiracetam. In this case we recommend AbsorbYourHealth as a trusted supplier.

Buy From AbsorbYourHealth


As you might have concluded, Oxiracetam poses formidable competition for many other nootropics on the market as most people who use cognitive enhancers consider it a must-have in their daily regimen of supplements.

Its enhancements cover a wide and varied array of cognitive processes as it helps with learning and memory formation, it enhances concentration, focus and awareness, and improves technical and logical thinking. Because of this, it is favored by researchers, writers, students or anybody else who needs continuously increased mental energy for prolonged periods of time.

Since it has a mildly stimulating effect on the central nervous system, it provides mental clarity and motivation as well as physical and mental energy without nasty withdrawal symptoms such as nervousness, mental cloudiness, sleepiness or any other negative side effects that are usually associated with CNS stimulants.

As we have already mentioned above, Oxiracetam is not toxic even at high doses which makes it an ideal starting point for anybody who wants to start exploring the world of cognitive enhancers. Because of the many benefits it provides, many veteran nootropic users also consider it to be irreplaceable in their daily regimen.


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